Run in the light :exploring exercise and photobiomodulation in Parkinson's disease /
"Version: 20190801"--Title page verso."A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso.Includes bibliographical references.1. Parkinson's disease -- 1.1. General -- 1.2. Signs and symptoms -- 1.3. The basal ganglia -- 1.4. Pathophysiology -- 1.5. Risk factors -- 1.6. Animal models -- 1.7. Current treatments -- 1.8. Neuroprotection and future treatments2. The run is exercise -- 2.1. General -- 2.2. Why should exercise work? -- 2.3. How much exercise do you need? -- 2.4. Methods of exercise : how do you do it? -- 2.5. Exercise-induced neuroprotection : a matter of survival -- 2.6. Exercise-induced symptomatic effects : a matter of function -- 2.7. Exercise-induced functional and behavioural improvements -- 2.8. Summary and a working hypothesis for a 'trigger'3. The light is photobiomodulation -- 3.1. General : what is light? -- 3.2. Light-induced neuroprotection : a matter of survival -- 3.3. Light-induced symptomatic effects : a matter of function -- 3.4. Light-induced functional and behavioural improvements in animal models of Parkinson's disease -- 3.5. How will light work in humans? -- 3.6. Light-induced changes in Parkinson's disease patients -- 3.7. The road to a therapeutic option for light treatment in patients -- 3.8. Why should light work? -- 3.9. Summary4. The run and the light : the dynamic duo -- 4.1. They are so similar -- 4.2. Potential benefits of a combined therapy : a cocktail -- 4.3. Is there a precedent? -- 4.4. A combined therapy protocol for Parkinson's disease patients? -- 4.5. Conclusions.Parkinson's disease is a neurological disorder with cardinal motor signs of resting tremor, bradykinesia and lead-pipe rigidity. In addition, many patients display non-motor symptoms, including a diminished sensation of smell, gastrointestinal problems, various disorders of sleep and some cognitive impairment. These clinical features manifest after a progressive death of many dopaminergic neurones in the brain. This book focuses on two therapies that are readily available for the patients of today. They involve the use of exercise and light (i.e. photobiomodulation, the use of red to infrared light therapy on body tissues). Part of IOP Series in Photomedicine and BiophotonicsGeneral/trade.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.John Mitrofanis gained his PhD at the University of Sydney. He is Professor of Anatomy at Sydney Medical School. Throughout his career he has been an active teacher of topographical anatomy and neuroanatomy to medical and science students and has run a research programme on brain organisation. His research has examined the structure and patterns of connectivity in the adult and developing thalamus, cortex and brainstem and he has explored different methods that improve the function and survival of neurones in Parkinson's disease.Title from PDF title page (viewed on September 5, 2019).
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