Cold plasma cancer therapy /

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"Version: 20190301"--Title page verso."A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso.Includes bibliographical references.1. Plasma as a fourth state of matter -- 1.1. Plasma types -- 2. Introduction to the non-thermal plasmas3. The anti-cancer effect of cold atmospheric plasma in vitro -- 3.1. The research status -- 3.2. The specific vulnerability of cancer cells to CAP -- 3.3. The long-term cellular responses -- 3.4. The selective anti-cancer effect -- 3.5. The short-term cellular responses4. The anti-cancer mechanism of cold atmospheric plasma in vitro -- 4.1. The activation of cancer cells -- 4.2. The reactive species -- 4.3. The rise of intracellular ROS -- 4.4. The selective anti-cancer mechanism5. The anti-cancer effect of CAP treatment in vivo -- 5.1. Introduction -- 5.2. The in vivo demonstration -- 5.3. The clinical demonstration -- 5.4. Mechanism -- 5.5. Reactive species and skin6. Indirect CAP treatment, the application of the cold atmospheric plasma-activated solutions in cancer treatment -- 6.1. Introduction -- 6.2. The CAP-activated medium -- 6.3. The reactive species in PAS -- 6.4. The principles to make PAS7. Adaptive plasmas and recent progress in plasma application in cancer therapy -- 7.1. Plasma self-organization phenomena -- 7.2. Adaptive plasma devices -- 7.3. MPC-based adaptive plasma platform8. Clinical applications of cold atmospheric plasma for glioblastoma -- 8.1. Introduction -- 8.2. Cold atmospheric plasma as a potential mediator of immune stimulation -- 8.3. Cold atmospheric plasma-mediated inflammation as a promoter of mesenchymal stem cell localization -- 8.4. Cold atmospheric plasma and nanoparticles applied as a synergistic cancer therapy -- 8.5. Facing forward : cold atmospheric plasma treatment of glioblastoma.Cold atmospheric plasma (CAP) has emerged as a possible new modality for cancer treatment. This book provides a comprehensive introduction into fundamentals of the CAP and plasma devices used in plasma medicine. An analysis of the mechanisms of plasma interaction with cancer and normal cells including description of possible mechanisms of plasma selectivity is included. Recent advances in the field, the primary challenges and future directions are presented.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Michael Keidar is the A. James Clark Professor of Engineering at George Washington University. His research concerns advanced spacecraft propulsion, plasma-based nanotechnology, and plasma medicine. He has authored over 260 journal articles and is the author of the book 'Plasma Engineering: Applications from Aerospace to Bio and Nanotechnology'. He received the 2017 Davidson award in plasma physics. In 2016, he received the AIAA Engineer of the Year award for his work on micropropulsion, resulting in the successful launch of a nanosatellite with thrusters developed by his laboratory. Dr. Dayun Yan obtained his MS degree (Mechanical Engineering) from Tsinghua University. After that, he worked as a research assistant in the State Key Laboratory of Tribology for two years. He later obtained his PhD (Mechanical Engineering) at the George Washington University in 2016 under the supervision of Dr Keidar, and then began his postdoctoral training there. His current research focuses on several core problems in plasma medicine, such as the activation phenomenon during the direct cold plasma effect on cancer cells. Jonathan H. Sherman, MD, FAANS, FACS is a neurosurgeon, associate professor, director of surgical neuro-oncology, and director of stereotactic radiosurgery at The George Washington University School of Medicine & Health Sciences. He obtained his medical degree from the Medical College of Georgia and completed his neurosurgery residency at the University of Virginia. Following completion of residency, he completed a fellowship in surgical neuro-oncology at Memorial Sloan-Kettering Cancer Center. His clinical interests include primary and metastatic brain tumors.Title from PDF title page (viewed on April 1, 2019).

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Series Title

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Call Number

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Publisher

: .,

Collation

1 online resource (various pagings) :illustrations (chiefly color).

Language

English

ISBN/ISSN

9781643274348

Classification

616.99406

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-

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-

Edition

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Subject(s)

Plasma physics.
Cancer
Neoplasms
SCIENCE / General.
Low temperature plasmas
Plasma Gases

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Statement of Responsibility

Michael Keidar, Dayun Yan and Jonathan H. Sherman.

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