Magnetic nanomaterials :innovation for cancer theranostics /

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Magnetic nanomaterials :innovation for cancer theranostics /

Mukherjee, Sudip, - Personal Name; Institute of Physics (Great Britain), - Personal Name; Madamsetty, Vijay Sagar, - Personal Name; Pradhan, Lipi, - Personal Name; Upadhyay, Anjali, - Personal Name; Yenurkar, Devyani, - Personal Name;

"Version: 20250501"--Title page verso.Includes bibliographical references.1. Introduction to magnetic nanomaterials -- 1.1. History of metallic nanoparticles -- 1.2. Applications of magnetic nanoparticles in cancer theranostics2. Synthesis of MNPs and their physicochemical characterization -- 2.1. Various methods for MNP synthesis -- 2.2. Physicochemical characterization of MNPs -- 2.3. Thermodynamic influences on MNP self-assembly and therapeutic uses -- 2.4. Use of MNPs in therapeutic applications -- 2.5. Hybrid MNPs and overall industrial manufacture3. Magnetic nanoparticles for cancer therapy -- 3.1. MNPs as drug delivery vehicles -- 3.2. MNPs as anticancer agents -- 3.3. Immunomodulation and immunotherapy by MNPs -- 3.4. MNP-mediated photothermal therapy -- 3.5. MNPs in photodynamic therapy -- 3.6. Magnetic-hyperthermia-based therapy -- 3.7. MNPs in cancer theranostics (diagnosis and therapy) -- 3.8. Combination of therapies using MNPs4. MNPs for cancer diagnosis and imaging -- 4.1. Overview of cancer diagnosis challenges -- 4.2. Role of magnetic nanoparticles as promising diagnostic tools -- 4.3. Magnetic resonance imaging -- 4.4. Fluorescence imaging -- 4.5. Optical imaging techniques -- 4.6. Multimodal imaging methods -- 4.7. Summary of the benefits of using magnetic nanoparticles in cancer diagnosis5. MNPs in clinical trials -- 5.1. Clinical trials of MNPs for imaging and diagnosis of cancer -- 5.2. Clinical trials of MNPs for therapeutic purposes in cancer -- 5.3. Patents filed on magnetic MNPs for advanced cancer theranostics6. Magnetic nanoparticles : biodistribution, excretion, toxicity, and overall conclusions -- 6.1. Biodistribution and excretion of MNPs -- 6.2. Conclusions.Full-text restricted to subscribers or individual document purchasers.Magnetic nanomaterials (MNPs) have emerged as a significant advancement in nanotechnology, attracting considerable attention for their effective applications in the biomedical field. This book explores various methods of synthesis and characterization, as well as the diverse applications of MNPs, with a primary focus on cancer theranostics. Their superparamagnetic properties allow for precise control and enhance imaging techniques such as MRI, which facilitates high-resolution tumor detection and monitoring. In therapeutic settings, MNPs are utilized for magnetic hyperthermia, generating localized heat to selectively destroy cancer cells. Additionally, they function as nanocarriers for targeted drug delivery, ensuring the precise release of therapeutic agents at tumor sites while minimizing systemic toxicity. This book offers a comprehensive overview of recent clinical trials involving various MNPs in cancer theranostics, highlighting both ongoing clinical studies and approved applications. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.Researchers, scientists and practitioners in biomaterials, magnetic nanomaterials, biopharmaceuticals and bioengineering for cancer research and immunotherapeutics.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Sudip Mukherjee, is an Assistant Professor at IIT (BHU), Varansi (India). He received his PhD in chemical sciences and nanomedicine at Calcutta University. From 2016-2020, he was a Postdoctoral Research Associate at Rice University in Houston, TX. His primary research is in magnetic nanomaterials and associated fields, where he has published 56 referred journal articles and been awarded 6 patents, with two pending. He is a member of the Royal Society of Chemistry, Associate Editor, Fronters in Chemistry (Section: Nanoscience), Associate Editor, BMC Cancer, UK, member of the International Advisory Board, Materials Research Express, IOP Publishing, UK and a member of the American Chemical Society. He is an editorial referee for eight different materials and nanomedicine journals. Vijay Sagar Madamsetty, received his PhD at the CSIR-Indian Institute of Chemical Technology and is currently employed as a Senior Scientist (Investigator) at CSL Seqirus Biopharmaceuticals, in Waltham MA (USA). Before that he was a postdoc for six years at the Mayo Clinic College of Medicine, where among other activities, he researched tumor targeted lipid nanoparticles which were established for effective delivery of CRISPr/RNA for pancreatic cancer treatment. Now his major work at CSL Seqoris deals with formulation support for preclinical studies and clinical trials, related the development of lipid nanoparticles, magnetic nanoparticles and nRNA degradation mechanisms. He has published 29 accepted refereed journal articles. Lipi Pradhan is a research scholar presently pursuing her PhD in the School of Biomedical Engineering, IIT BHU, Varanasi. She has earned her MSc in zoology from the Department of Zoology, Ranchi University. Her research interests involve designing cell-based therapy for treating rare genetic disorders and green synthesis of nanoparticles for various biomedical applications. Anjali Upadhyay is a research scholar pursuing her PhD from the School of Biomedical Engineering, IIT BHU, Varanasi. She did her master's (MSc) from the University of Allahabad (Department of Zoology). Her research interests include inorganic biomaterials for antifibrotic, antibacterial, and antibiofilm applications. Devyani Yenurkar is a Prime Minister's Research Fellow (PMRF) in the School of Biomedical Engineering at the Indian Institute of Technology IIT(BHU). She received her master's in pharmacy (pharmaceutics) from SNDT University, Mumbai. Her present interests in research include work with nanomaterials for their potential applications in the field of blood anticoagulation and thrombosis.Title from PDF title page (viewed on June 2, 2025).

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Series Title: -
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Publisher: : .,
Collation: 1 online resource (various pagings) :illustrations (some color).
Language: English
ISBN/ISSN: 9780750363358
Classification: 616.99406
Content Type: -
Media Type: -
Carrier Type: -
Edition: -
Subject(s): Nanostructures
Nanostructured materials
Cancer
Neoplasms
Nanomedicine.
Oncology.
Magnetic materials.
Theranostic Nanomedicine
Magnetic Phenomena.
MEDICAL / Chemotherapy.
Specific Detail Info: -
Statement of Responsibility: Sudip Mukherjee, Vijay Sagar Madamsetty, Lipi Pradhan, Anjali Upadhyay, Devyani Yenurkar.

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