Open-channel microfluidics :fundamentals and applications /

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"Version: 20240401"--Title page verso.Includes bibliographical references.Introduction : open-channel microfluidics and open microfluidics -- 1. The theoretical basis of capillarity -- 1.1. Introduction2. The Lucas-Washburn-Bosanquet approach -- 2.1. Introduction -- 2.2. The Bosanquet equation -- 2.3. Simplification : inertial and viscous regimes -- 2.4. The full Bosanquet solution -- 2.5. Correcting for the dynamic contact angle -- 2.6. Conclusions3. Condition for capillary flow in open channels -- 3.1. Spontaneous capillary flow in a monolithic channel -- 3.2. Spontaneous capillary flow in composite open channels : the generalized Cassie condition -- 3.3. Common geometries -- 3.4. Enhanced open-capillary flows -- 3.5. Conclusions4. Flow dynamics in open channels of uniform cross-section -- 4.1. Spontaneous capillary flow in composite, closed channels of arbitrary uniform cross-section -- 4.2. Spontaneous capillary flow in open channels of arbitrary uniform cross-section -- 4.3. The dynamic contact angle -- 4.4. Rough walls -- 4.5. A summary of the dynamics of capillary flow in an open channel -- 4.6. The capillary dynamics of non-Newtonian fluids -- 4.7. Representation in 1/V5. Common open-channel geometries -- 5.1. Introduction -- 5.2. Suspended channels -- 5.3. Rails -- 5.4. Rectangular channels -- 5.5. Rounded channels -- 5.6. Semicylindrical channels -- 5.7. Embossed channels -- 5.8. Fiber bundles and flow caging -- 5.9. Capillary rise and uphill open-capillary flows -- 5.10. Conclusions6. Capillary filaments -- 6.1. Introduction -- 6.2. Capillary filaments : the Concus-Finn condition -- 6.3. The case of V-grooves -- 6.4. Capillary filaments in open-channel turns -- 6.5. Capillary filaments in nonuniform channels -- 6.6. Detached capillary filaments -- 6.7. Metastable capillary filaments -- 6.8. Capillary filaments driving spontaneous capillary flow -- 6.9. The dynamics of capillary filaments -- 6.10. The drying of capillary filaments -- 6.11. Capillary filaments stopped by rounded wedges -- 6.12. Conclusions7. Flow in open channels of nonuniform cross-section -- 7.1. Static aspects -- 7.2. Dynamic aspects -- 7.3. Bifurcations and networks -- 7.4. Filters -- 7.5. Open deterministic lateral devices -- 7.6. Example of blood plasma separation in a diverging channel -- 7.7. Conclusions8. Capillary flow in fibrous media -- 8.1. Parameters characterizing the capillary flow in fibrous media -- 8.2. Flow dynamics in fibrous media -- 8.3. Determining porosity, permeability, and capillary pressure -- 8.4. Equivalent permeability -- 8.5. Flow velocity in paper strips of varying width -- 8.6. Open channels connected to paper pads -- 8.7. Conclusions9. Biomimetics--open microfluidics in nature -- 9.1. Introduction -- 9.2. Open channels on Dryopteris marginata leaves -- 9.3. Flow alongside Sarracenia trichomes -- 9.4. Directional spreading on natural surfaces -- 9.5. Conclusions10. Two-phase open-channel capillary flows -- 10.1. Introduction -- 10.2. Part 1 : plugs and droplets in open channels of uniform cross-section -- 10.3. Part 2 : the production and manipulation of droplets -- 10.4. Conclusions11. Applications -- 11.1. Introduction -- 11.2. Materials and fabrication -- 11.3. Microfluidic channels -- 11.4. Biology, biotechnology, and medicine -- 11.5. Biosensors -- 11.6. A space-based application--the space cup -- 11.7. Conclusions12. Open-capillary fluidics aboard spacecraft -- 12.1. Introduction -- 12.2. Statics : configurations, initial conditions, and stability -- 12.3. Dynamics : inertia and bubble separations -- 12.4. Applications of open macrofluidics aboard spacecraft -- 12.5. Conclusions -- 13. Epilogue.Full-text restricted to subscribers or individual document purchasers.The development of open microfluidics is relatively recent and is an emerging sub-domain of capillarity, with many applications. This second edition research text presents the state-of-the-art theory of open microfluidics, including inertial and viscous regimes, uniform channels and converging/diverging channels, networks, bypasses and valves. It recalls the conditions for the establishment of an open microflow, and presents the dynamics of open microflows, guided by different solid structures such as fibres and threads, with a focus on open-channels. The book shows how the Lucas-Washburn law must be adapted to describe the dynamics of open microflows. It also demonstrates how surface energies, fluid properties, and solid geometry are combined to design open-microfluidic systems and devices that are used in numerous domains. Additionally, the book shows how biomimetics has inspired new advanced open microfluidic designs.Researchers, industry practitioners and advanced students working on microfluidics.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Jean Berthier is an Affiliate Professor at the University of Washington, Seattle, USA. He received an MS in Mathematics from the University of Grenoble, an engineering diploma from the Institut National Polytechnique in Grenoble, and a PhD from the University Pierre et Marie Curie in Paris. After spending four years at Sandia and Los Alamos National laboratories focused on the interaction between liquid and gases, he joined the CEA-Leti in Grenoble, France, where he was involved in the development of microfluidic solutions for liquid-liquid extraction, bio-encapsulation of living cells, capillary solutions for portable point-of-care devices. Ashleigh Theberge is an Associate Professor of Chemistry at the University of Washington and Adjunct Associate Professor of Urology at the University of Washington School of Medicine. She received a BA in Chemistry from Williams College and a PhD in Chemistry from the University of Cambridge, UK, with Wilhelm Huck in droplet-based microfluidics. Her work focuses on using open microfluidics to study cell signaling, to create new methods for three dimensional tissue patterning, and to develop technologies for remote sampling of blood, saliva, and air for diagnostics and decentralized clinical research. Erwin Berthier is presently Affiliate Associate Professor at the University of Washington in Seattle. He is also co-founder and CTO of Tasso Inc., a Seattle-based company developing patient-centric, distributed health technologies. He received a Diplome d'Ingenieur in Fluid Mechanics from ENSTA (Ecole Nationale Sup?erieure des Technologies Avanc?ees) in Paris, a Masters of Electrical Engineering from the University of Canterbury (New Zealand), and a PhD in Biomedical Engineering from the University of Wisconsin in Madison. His current research interests focus on advancing the theory and applications of open microfluidics as well as distributed sensing technologies for healthcare applications, agriculture, and public health.Title from PDF title page (viewed on May 1, 2024).

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Publisher

: .,

Collation

1 online resource (various pagings) :illustrations (some color).

Language

English

ISBN/ISSN

9780750355070

Classification

629.8/042

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-

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-

Edition

Second edition.

Subject(s)

SCIENCE / Mechanics / Fluids.
Microfluidics.
Mechanics of fluids.

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Statement of Responsibility

Jean Berthier, Ashleigh B. Theberge, Erwin Berthier ; with contribution from Mark Weislogel.

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