Aptasensors for point-of-care diagnostics of cancer :from lab to clinics /

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"Version: 20231101"--Title page verso.Includes bibliographical references.1. Aptamer-based point-of-care testing : an overview from past to future / Rajesh Ahirwar and Nabab Khan -- 2. Point-of-care systems : brief history to recent advances in the field of cancer / Sayali Mukherjee and Tanushree Sharma -- 3. Aptasensors for cancer diagnostics : an insight into immobilization strategies / Pushpesh Ranjan, Rudramani Tiwari, Lal Singh Banjara, Mohd Abubakar Sadique, Shalu Yadav, Raju Khan, S. Krishnamoorthi, Ajay Kumar Meena and Subhash Chandra Verma -- 4. Rapid detection of circulating cancer cells point-of-care diagnostic using aptasensors / Shagun Gupta, Surbhi Sharma, Deepak Kala and Ankur Kaushal -- 5. Aptamer-based bioassays using proteins/biomarkers : a critical role of cancer point-of-care testing / Pushpesh Ranjan, Lal Singh Banjara, Shalu Yadav, Mohd. Abubakar Sadique, Raju Khan and Rudramani Tiwari -- 6. Cancer diagnostics the synthesis and selection of aptamers for diagnostic applications / Rudramani Tiwari, Pushpesh Ranjan, Shalu Yadav, Mohd Abubakar Sadique, Raju Khan, S. Krishnamoorthi, Ajay Kumar Meena and Subhash Chandra Verma -- 7. Aptasensors for point-of-care diagnostics of cancer / Deepshikha Shahdeo and Sonu Gandhi -- 8. Optical aptasensors for the early diagnosis of cancer biomarkers / Debanjan Ghosh, Sakshi Hardaha, Aadil Ashraf and Soumyadeep Mukherjee -- 9. Lab-on-a-chip systems for aptamer-based cancer biomarker screening / Ali Firoozbakhtian, Morteza Hosseini, Javad Gilnezhad and Mohammad Reza Ganjali -- 10. Nanotechnology in cancer diagnosis : challenges and opportunitiesn / Arpana Parihar, Kritika Gaur and Raju Khan -- 11. Current perspectives on aptasensors as diagnostic tool for cancer screening / Shagun Gupta, Deepak Kala, Nkurunziza Florien, Surbhi Sharma and Ankur Kaushal -- 12. Applications of nucleic acid aptamers in cancer diagnostics from the laboratory to the clinic / Enamala Manoj Kumar, Supraja Enamala, Rishibha Dixit, S.M. Faheem, Payal B. Joshi and Murthy Chavali.The aptasensor-based point-of-care testing devices offer high sensitivity and specificity They are cost-effective, provide rapid detection, and are stable in an adverse environment, making them suitable tools for on-site detection of cancer biomarkers in medical and clinical settings. The book emphasizes the target-specific design, functionalization, and synthesis of aptamers for the fabrication of aptamer-based biosensors which can be employed for cancer biomarkers detection. This book will provide the reader with a timely update on the recent advances in aptamers-based point-of-care biosensors for cancer diagnostics. It will also demonstrate the advantages of aptamers such as low cost, ease of design, synthesis, and modification, hence can be employed as a good alternative to antibody-based biosensors. It will also shed light on nanostructured materials and their significance for the construction of point-of-care aptasensors. Furthermore, it will describe in detail the integration of a point-of-care aptasensors-based sensing platform integrated with a wireless platform (internet of medical things) for intelligent disease management. Part of IOP Series in Global Health and Radiation Oncology.Clinicians, researchers, scientists in point-of-care diagnostics and technologies.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Arpana Parihar is a DST Women Scientist-B at the CSIR-Advanced Materials and Processes Research Institute in Bhopal, India. She has over eight years of research experience at various institutions such as RRCAT Indore, IIT Delhi, etc, particularly in the field of cancer theragnostics. Her current research interest includes the fabrication of biosensors for early diagnosis of cancer and infectious diseases. She also contributed significantly in the fields of, stem cell biology, tissue engineering, targeted therapy, and photodynamic therapy of cancer. She has published over 35 referred journal articles, 25 book chapters, and five books. Pushpesh Ranjan is currently working as a PhD candidate at CSIR-Advanced Materials and Processes Research Institute (AMPRI) under the supervision of Dr. Raju Khan at the Industrial Waste Utilization, Nano and Biomaterials division. His current research is focused on the development of graphene oxide-ionic liquid-based nano biosensors, along with aptasensor-based point-of-care biosensors. He had over five years of research experience at CSIR-AMPRI Bhopal and IIT Indore. He has published over 19 refereed journal articles and >10 book chapters. Raju Khan is a Senior Principal Scientist and Professor at CSIR-Advanced Materials and Processes Research Institute. His current research focuses on electrochemical biosensor point-of-care diagnostics, integrated with microfluidics for clinical applications. He has more than 15 years of R&D experience in CSIR and other academic institutions. He has also been a visiting scientist at the University of Texas at San Antonio. He has published more than 81 refereed journal articles, which have attracted more than >3900 citations, >25 book chapters, and been the editor of 10 books with Elsevier and Taylor & Francis.Title from PDF title page (viewed on January 4, 2024).

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Publisher

: .,

Collation

1 online resource (various pagings) :illustrations (some color).

Language

English

ISBN/ISSN

9780750350129

Classification

616.99/4075

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Subject(s)

Cancer
Neoplasms
Biosensors.
Biosensing Techniques.
Oncology.
MEDICAL / Oncology / General.

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Statement of Responsibility

edited by Arpana Parihar, Pushpesh Ranjan, Raju Khan.

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