Spatially fractionated, microbeam and FLASH radiation therapy :a physics and multi-disciplinary approach /

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"Version: 202306"--Title page verso.Includes bibliographical references.part I. Biology and clinical use. 1. Introduction to the principles of spatially fractionated radiotherapy / Karl T. Butterworth, Yolanda Prezado and Kevin M. Prise -- 2. General principles of SFRT biology / Andrew J. Johnsrud, Samir V. Jenkins and Robert J. Griffin -- 3. The immunologic effects of nonuniform dose irradiation / Ariel E. Marciscano, Encouse B. Golden and Silvia C. Formenti -- 4. The biology of FLASH--a critical appraisal for clinical translation / Veljko Grilj and Marie-Catherine Vozenin -- 5. SFRT experience in multi-disease studies of voluminous and metastatic tumors / Gregory S. Alexander, Dan K. Kunaprayoon and William F. Regine -- 6. GRID spatially fractionated radiation therapy : definitive radiation therapy in bulky primary tumors / Majid Mohiuddin, James W. Snider and Jos?e Pe?anagar?icano -- 7. Lattice Radiotherapy SFRT : definitive radiation therapy in bulky primary tumors / Beatriz E. Amendola, Naipy C. Perez, Benhua Xu, Nina A Mayr, Marco A. Amendola and Xiaodong Wu -- 8. Proton beam spatially fractionated radiation therapy : clinical data / Ronald Chow, Minglei Kang and Charles B. Simone, IIpart II. Physics of moderate dose rate SFRT. 9. GRID-collimator-based and static-field SFRT / Hualin Zhang -- 10. The technical aspects of 3D lattice radiation therapy (LRT) / Xiaodong Wu, Naipy C. Perez, Xiaobo Li, Beatriz E. Amendola, Georges F. Hatoum and Benhua Xu -- 11. Rotational arc SFRT / Xin Zhang, Jos?e Pe?anagar?icano and Eduardo G. Moros -- 12. Electron beam SFRT / Hajime Monzen and Mikoto Tamura -- 13. Proton beam spatially fractionated radiotherapy / Mingcheng Gao and Mark Pankuch -- 14. Radiobiological modeling and equivalent uniform dose for spatially fractionated radiation therapy / Stefan H. Bartzsch, Robert D. Stewart and Juergen Meyer -- 15. Spatially fractionated radiation therapy field calibration and commissioning / Michael Grams and Hualin Zhang -- 16. SFRT dose prescription / Nina A. Mayr, Beatriz E. Amendola, James S. Welsh, Hualin Zhang, Naipy C. Perez, Xiaodong Wu and Simon S. Lo -- 17. SFRT dosimetric parameters and their associations with treatment response / Sha X. Chang and Robert J. Griffin -- 18. Monte Carlo simulation of photon beam spatially fractionated radiotherapy / Immaculada Mart?inez-Rovira and Jos?e M Fern?andez-Varea -- 19. Monte Carlo simulation of proton SFRT / Tim Schneider, Ludovic De Marzi and Ram?on Ortizpart III. Physics of microbeam, minibeam SFRT and ultra-high dose rate FLASH therapy. 20. Microbeam SFRT with photons / Valentin Djonov, Cristian Fernandez-Palomo and Paolo Pellicioli -- 21. Spatially fractionated radiation therapy : from photons to charged particles / Yolanda Prezado -- 22. Ultra-high dose-rate electron FLASH radiation therapy / Peter G. Maxim, Emil Sch?uler and Kristoffer Petersson -- 23. The use of synchrotrons in SFRT and FLASH therapy / Audrey Bouchet and Marine Potez -- Conclusions / Charles L. Limoli, Charles B Simone II, Nina A Mayr and Hualin Zhang -- Glossary of spatially fractionated and FLASH radiation therapy / Juergen Meyer, Yolanda Prezado, Hualin Zhang and Nina A. Mayr.This textbook is a comprehensive review of the physics of heterogeneous radiation and is linked, through a multidisciplinary approach, to clinical applications and biological considerations of heterogenous radiation. Fundamental principles of Spatially Fractionated Radiation Therapy (SFRT), techniques and technologies, dosimetric properties of SFRT, planning methods, documentation, standardized reporting metrics and clinical practice recommendations are comprehensively reviewed. The current status and results of clinical patient studies are presented, which have the potential to advance the management of bulky and advanced tumors. Potential biological underpinnings are reviewed that may challenge the current radiobiological understanding of radiation response and radiation therapy design parameters. Such multidisciplinary understanding is a critical foundation as the field of heterogeneous radiation rapidly advances in technological development and clinical investigation. Part of IPEM-IOP Series in Physics and Engineering in Medicine and Biology.Researchers, practitioners, clinicians in radiation oncology, radiology, medical physics and radiation therapy.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.Hualin Zhang, PhD is an Associate Professor in the Department of Radiation Oncology at the University of Southern California. Prior to that he held the position of the chief physicist of brachytherapy in the Department of Radiation Oncology at Northwestern University Feinberg School of Medicine. He serves as chair of the Radiosurgery Society GRID/Lattice, Microbeam and FLASH Radiation Therapy Physics Working Group; and as the chair of the AAPM Intraoperative Mesh Brachytherapy Working Group. He has published over 50 peer reviewed journal articles. He is recipient of the Outstanding Teacher Award there in 2018. Nina A Mayr, MD is Professor and Senior Academic Advisor in the Office of Health Sciences at Michigan State University. She previously served as chair of Department of Radiation Oncology and endowed professor in the University of Washington School of Medicine. Her specialities include advanced radiation therapy modalities; imaging and image-guided radiation; and imaging predictors of cancer treatment outcomes, for which she received two R01 grant awards; women cancers; lung cancer and neuro radiation oncology. She serves as chair of the Radiosurgery Society GRID/Lattice, Microbeam and FLASH Radiation Therapy Clinical Working Group. She has been awarded the elected Fellow of the American Association of the Advancement of Science (AAAS), Fellow of ASTRO, and the American Board of Radiology Lifetime Service Award for her contributions to research and education. She has published over 200 journal articles.Title from PDF title page (viewed on July 6, 2023).

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: .,

Collation

1 online resource (various pagings) :illustrations (some color).

Language

English

ISBN/ISSN

9780750340465

Classification

616.9940642

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-

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-

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Subject(s)

Medical physics.
Cancer
Neoplasms
Radiation Oncology
Medicine.
MEDICAL / Oncology / General.

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Statement of Responsibility

edited by Hualin Zhang, Nina A. Mayr.

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