Foundations of regenerative biology and medicine /

---

"Version: 20181001"--Title page verso.Includes bibliographical references.part I. Regenerative biology. 1. Regeneration -- 1.1. Introduction -- 1.2. Who and what regenerates? -- 1.3. A brief history of regenerative biology -- 1.4. The regenerative niche -- 1.5. Approaches to the study of regeneration -- 1.6. Mechanisms of regeneration -- 1.7. Transdifferentiation -- 1.8. Regeneration by adult stem cells -- 1.9. Some tissues use multiple mechanisms of regeneration2. Wound repair by fibrosis -- 2.1. Fibrosis is studied primarily in skin -- 2.2. Structure and function of skin -- 2.3. Types of wounds -- 2.4. Stages of repair in acute wounds -- 2.5. Aging reduces the repair capacity of acute skin wounds -- 2.6. Chronic wounds fail to heal -- 2.7. Non-scarring skin repair models -- 2.8. Comparative molecular analysis of wound repair and regeneration3. Regeneration by adult stem cells -- 3.1. Epithelial stem cells -- 3.2. Mesenchymal stem cells -- 3.3. Stem cells in non-regenerating organs4. Non-stem cell regenerative mechanisms -- 4.1. Cellular re-growth: axon regeneration -- 4.2. Regeneration from pre-existing differentiated cells -- 4.3. Transdifferentiation: newt lens and retina5. Appendage regeneration -- 5.1. Limb regeneration in urodele amphibians -- 5.2. Appendage regeneration in Xenopus -- 5.3. Mouse digit tip regeneration -- 5.4. Regeneration of mouse ear tissue -- 5.5. Regeneration of deer antlers -- 5.6. Enhancement of appendage regenerationpart II. Regenerative medicine. 6. Strategies of regenerative medicine -- 6.1. Historical notes -- 6.2. Biomimetic devices and organ transplants -- 6.3. Pharmaceutical induction of regeneration in situ -- 6.4. Cell transplants -- 6.5. Biomimetic tissues7. Pharmaceutical therapies for wound repair and regeneration -- 7.1. Skin -- 7.2. Neural tissues -- 7.3. Musculoskeletal tissues -- 7.4. Cardiac muscle8. Cell transplants as regenerative therapy -- 8.1. Skin -- 8.2. Neural tissues -- 8.3. Liver and pancreas -- 8.4. Musculoskeletal tissues -- 8.5. Cardiac tissues -- 8.6. Hematopoietic deficiency disorders9. Biomimetic tissues and organs -- 9.1. Skin -- 9.2. Muscle -- 9.3. Bone -- 9.4. Articular cartilage -- 9.5. Cardiovascular tissue -- 9.6. Liver and pancreas -- 9.7. Airways -- 9.8. Kidney and bladder10. Into the adjacent possible -- 10.1. Technical innovations -- 10.2. Applications of edge technologies -- 10.3. Bioethics in regenerative medicine -- 10.4. Concluding statement.Regenerative biology and medicine is a rapidly developing field that can revolutionize medicine. It is a nexus of convergent science, drawing from chemistry, physics, mathematics and bioengineering. Foundations of Regenerative Biology and Medicine introduces the essentials of regenerative biology and medicine to advanced undergraduates and beginning graduate students, as well as students and professionals outside the field who need (and want) an introduction to the subject. This relatively short ten chapter book can be read in one semester and delivers the essential framework to understand the biological aspects of different mechanisms of regeneration and the therapeutic strategies that have emerged from this biology.Advanced undergraduate biology majors, beginning biology graduate students, chemistry, physics or bioengineering students.Also available in print.Mode of access: World Wide Web.System requirements: Adobe Acrobat Reader, EPUB reader, or Kindle reader.David L Stocum is Emeritus Professor of Biology and Emeritus Dean of the School of Science at Indiana University-Purdue University Indianapolis. He holds undergraduate degrees in Biology and Psychology from Susquehanna University, a MS in Zoology from the University of Illinois at Urbana-Champaign and a PhD in Cell and Developmental Biology from the University of Pennsylvania. He pursued an active research and teaching career in the School of Life Sciences at the University of Illinois Urbana-Champaign for 21 years, where he also served administrative terms as Director of the Honors Biology Program and Acting Head of Anatomical Sciences. Subsequently he served as Dean of the School of Science at Indiana University-Purdue University Indianapolis for fifteen years, and then another ten years as Professor in the Department of Biology, during which he also held an appointment as Affiliate and Research Scholar in the Regeneration Theme of the Carl Woese Institute for Genomic Biology at the University of Illinois, Urbana-Champaign. Dr. Stocum is known for his research on the regeneration of amphibian limbs, and for his writings on the general subject of regenerative biology and medicine.Title from PDF title page (viewed on November 8, 2018).

---

Availability

No copy data

Detail Information

Series Title

-

Call Number

-

Publisher

: .,

Collation

1 online resource (various pagings) :illustrations (some color).

Language

English

ISBN/ISSN

9780750316262

Classification

610. 28

Content Type

-

Media Type

-

Carrier Type

-

Edition

-

Subject(s)

Biomedical engineering.
TECHNOLOGY & ENGINEERING / Biomedical.
Regenerative medicine.
Tissue engineering.

Specific Detail Info

-

Statement of Responsibility

David L. Stocum.

Other version/related

File Attachment

Comments

---

You must be logged in to post a comment