"Version: 20230401"--Title page verso.Includes bibliographical references.1. Introduction -- 1.1. Early developments of biomedical engineering -- 1.2. Modelling in biomedical engineering -- 1.3. Modelling approaches in biomedical engineering2. Mechanistic modelling -- 2.1. Background -- 2.2. Fundamentals of mechanistic modelling -- 2.3. Ocular heat transfer : an illustrative example -- 2.4. Imp…